Description

3,4-Dihydro-2H-Pyrano[2,3-B]Pyridin-4-Ol is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a key chiral intermediate for constructing complex molecular architectures, particularly in the pharmaceutical sector. It is primarily sought after by R&D chemists and process development teams in the fine chemical and active pharmaceutical ingredient (API) manufacturing industries.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the development of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Organic Synthesis Building Block: Used in complex multi-step syntheses, including cyclization and coupling reactions, to introduce the fused pyrano-pyridine scaffold.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new catalytic systems due to its defined stereochemistry.
• Agrochemical Research: Serves as an intermediate in the synthesis of advanced crop protection chemicals with specific biological activity.
• Material Science Precursor: Potential use in the synthesis of organic ligands for metal-organic frameworks (MOFs) or functional polymers.

Basic Information

Product Name	3,4-Dihydro-2H-Pyrano[2,3-B]Pyridin-4-Ol
CAS No.	911826-21-6
Molecular Formula	C8H9NO2
Molecular Weight	151.16 g/mol
Synonyms	4-Hydroxy-3,4-dihydro-2H-pyrano[2,3-b]pyridine; 2H-Pyrano[2,3-b]pyridin-4-ol, 3,4-dihydro-; 4-Hydroxydihydropyranopyridine; Pyrano[2,3-b]pyridin-4-ol derivative; CAS 911826-21-6
EINECS	Contact for details

Quality Control

Our 3,4-Dihydro-2H-Pyrano[2,3-B]Pyridin-4-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent moisture absorption and oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.