Description

(R)-6-Fluorochroman-4-Amine Hydrochloride CAS NO 911826-09-0 is a high-purity chiral building block and pharmaceutical intermediate. This compound is of significant value for the development of novel active pharmaceutical ingredients (APIs), particularly in the central nervous system (CNS) and cardiovascular therapeutic areas. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and synthesis of novel drug candidates.
• Asymmetric Synthesis: Used in the construction of complex molecules requiring the (R)-enantiomer of the 6-fluorochroman-4-amine scaffold.
• Medicinal Chemistry Research: Serves as a core structure for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Employed as an analytical standard for quality control and method development in API manufacturing.
• Preclinical Development: Utilized in the production of compounds for pharmacological and toxicological evaluation.

Basic Information

Product Name	(R)-6-Fluorochroman-4-Amine Hydrochloride
CAS No.	911826-09-0
Molecular Formula	C9H11ClFNO
Molecular Weight	203.64 g/mol
Synonyms	(R)-6-Fluoro-3,4-dihydro-2H-1-benzopyran-4-amine hydrochloride; (4R)-6-Fluoro-3,4-dihydro-2H-chromen-4-amine hydrochloride; (R)-6-Fluoro-4-aminochroman hydrochloride; (R)-4-Amino-6-fluorochroman hydrochloride; 6-Fluorochroman-4-amine, (R)-, hydrochloride; (R)-6-Fluorochroman-4-amine HCl
EINECS	Contact for details

Quality Control

Our (R)-6-Fluorochroman-4-Amine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.