Description

4-Amino-Chroman-6-Carbonitrile Hydrochloride is a high-purity, pharmaceutically relevant organic building block. This compound matters as a key chiral intermediate in the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs), leveraging its amino and nitrile functional groups for further derivatization.
• Agrochemical Research: Serves as a building block for developing new agrochemicals and pesticides, where the chroman scaffold is of significant interest.
• Fine Chemical Production: Employed in the manufacture of specialty and fine chemicals requiring high-purity, structurally defined intermediates.
• Chemical Biology & Proteomics: Useful as a scaffold or labeling agent in chemical biology research for studying protein interactions and enzyme mechanisms.
• Academic & Industrial R&D: A valuable compound for methodological development in organic synthesis and catalysis studies within academic and industrial R&D laboratories.

Basic Information

Product Name	4-Amino-Chroman-6-Carbonitrile Hydrochloride
CAS No.	911825-88-2
Molecular Formula	C10H11N2O·HCl
Molecular Weight	210.67 g/mol (Free base: 175.21 g/mol)
Synonyms	4-Amino-3,4-dihydro-2H-1-benzopyran-6-carbonitrile hydrochloride; 6-Cyano-4-aminochroman hydrochloride; 4-Amino-6-cyanochroman hydrochloride; 4-Aminochroman-6-carbonitrile HCl; 2H-1-Benzopyran-6-carbonitrile, 4-amino-3,4-dihydro-, hydrochloride; 4-Amino-3,4-dihydro-2H-chromene-6-carbonitrile hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Amino-Chroman-6-Carbonitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Purity (HPLC, Area %)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.