Description

4-Amino-Chroman-8-Carbonitrile Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 911824-58-3. This compound is a critical building block in the synthesis of complex organic molecules, valued for its specific chroman ring structure and functional groups that enable targeted chemical transformations. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel therapeutic compounds, particularly those targeting central nervous system (CNS) disorders.
• Organic Synthesis Building Block: Utilized in medicinal chemistry for constructing complex heterocyclic frameworks due to its amino and nitrile functionalities.
• Research & Development (R&D): Serves as a critical reagent in academic and industrial R&D labs for exploring new chemical entities and reaction pathways.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals and high-value agrochemical intermediates.

Basic Information

Product Name	4-Amino-Chroman-8-Carbonitrile Hydrochloride
CAS No.	911824-58-3
Molecular Formula	C10H11N2O·HCl
Molecular Weight	210.67 g/mol (Free base: 175.21 g/mol)
Synonyms	8-Cyano-4-aminochroman hydrochloride; 4-Amino-8-cyanochroman hydrochloride; 4-Amino-3,4-dihydro-2H-1-benzopyran-8-carbonitrile hydrochloride; 2H-1-Benzopyran-8-carbonitrile, 4-amino-3,4-dihydro-, hydrochloride; Chroman-8-carbonitrile, 4-amino-, hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Amino-Chroman-8-Carbonitrile Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to prevent degradation from moisture and light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.