Description

1H-Indazole,7-(1-Piperazinyl)-,Hydrochloride is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is of significant interest for its role as a key building block in the synthesis of novel bioactive molecules, particularly in medicinal chemistry. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, especially within oncology and CNS research.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted small-molecule drugs and investigational new chemical entities (NCEs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Kinase Inhibitor Development: Used in the research and development of potential kinase inhibitors due to the indazole-piperazine pharmacophore.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard in pharmacological studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-scale production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental organic synthesis and bioorganic chemistry projects.

Basic Information

Product Name	1H-Indazole,7-(1-Piperazinyl)-,Hydrochloride
CAS No.	911643-93-1
Molecular Formula	C11H15ClN4
Molecular Weight	238.72 g/mol
Synonyms	7-Piperazin-1-yl-1H-indazole hydrochloride; 7-(1-Piperazinyl)-1H-indazole hydrochloride; 1H-Indazole-7-piperazine hydrochloride; 7-Piperazinylindazole HCl; 1H-Indazol-7-yl-piperazine hydrochloride; 7-(Piperazin-1-yl)-1H-indazole hydrochloride; 1H-Indazole, 7-(1-piperazinyl)-, monohydrochloride
EINECS	Contact for details

Quality Control

Our 1H-Indazole,7-(1-Piperazinyl)-,Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to maintain product integrity and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.