Description

3-T-Butoxycarbonylamino-4-(5,5-Difluoro-2-Oxo-Piperidin-1-Yl)Butyric Acid T-Butyl Ester is a sophisticated, high-purity chemical intermediate designed for advanced organic synthesis. This compound is valued for its role as a key building block in the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research. It is primarily sought after by pharmaceutical R&D departments and fine chemical manufacturers engaged in the synthesis of complex, fluorinated heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Used as a versatile building block for constructing complex molecular scaffolds with integrated piperidinone and fluorinated motifs.
• Protease Inhibitor Development: Serves as a key component in the research and development of enzyme inhibitors due to its specific structural features.
• Peptidomimetic Synthesis: Employed in the creation of peptide-like molecules with enhanced stability and bioavailability.
• Chemical Biology Probes: Utilized in the design and synthesis of labeled compounds for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	3-T-Butoxycarbonylamino-4-(5,5-Difluoro-2-Oxo-Piperidin-1-Yl)Butyric Acid T-Butyl Ester
CAS No.	911635-42-2
Molecular Formula	C19H32F2N2O5
Molecular Weight	406.47 g/mol
Synonyms	1,1-Difluoro-5-[(3-{[(tert-butoxy)carbonyl]amino}-4-[(tert-butoxy)carbonyl]butyl]piperidin-2-one; Boc-4-(5,5-Difluoro-2-oxopiperidin-1-yl)butylamine tert-Butyl Ester; tert-Butyl 3-((tert-butoxycarbonyl)amino)-4-(5,5-difluoro-2-oxopiperidin-1-yl)butanoate; 3-(Boc-amino)-4-(5,5-difluoro-2-oxo-1-piperidinyl)butyric Acid tert-Butyl Ester; 3-((tert-Butoxycarbonyl)amino)-4-(5,5-difluoro-2-oxopiperidin-1-yl)butanoic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our production of 3-T-Butoxycarbonylamino-4-(5,5-Difluoro-2-Oxo-Piperidin-1-Yl)Butyric Acid T-Butyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.