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(1R,2R)-2-Amino-1-(4-Iodophenyl)Propane-1,3-Diol CAS NO 911474-86-7


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CAS No.:911474-86-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(1R,2R)-2-Amino-1-(4-Iodophenyl)Propane-1,3-Diol is a chiral amino diol derivative featuring an iodophenyl group, serving as a high-value synthetic intermediate. This compound is critical for the development of enantiomerically pure pharmaceuticals and advanced materials due to its defined stereochemistry and functional handles. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications in asymmetric synthesis and as a building block for active pharmaceutical ingredients (APIs).

Application

  • Pharmaceutical Intermediate: Key chiral building block for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
  • Asymmetric Catalyst Ligand Precursor: Used in the development of chiral ligands for transition metal catalysis to control stereoselectivity in organic reactions.
  • Agrochemical Research: Intermediate in the synthesis of novel, optically active pesticides and herbicides.
  • Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a molecular scaffold.
  • Material Science: Potential monomer for synthesizing specialized polymers with unique optical or electronic properties.
  • Academic & Process R&D: Serves as a reference standard and starting material for novel synthetic route development in laboratory-scale research.

Basic Information

Product Name (1R,2R)-2-Amino-1-(4-Iodophenyl)Propane-1,3-Diol
CAS No. 911474-86-7
Molecular Formula C9H12INO2
Molecular Weight 293.10 g/mol
Synonyms (1R,2R)-1-(4-Iodophenyl)-2-aminopropane-1,3-diol; (1R,2R)-2-Amino-1-(4-iodophenyl)-1,3-propanediol; (1R,2R)-1-(p-Iodophenyl)-2-amino-1,3-propanediol; (1R,2R)-Amino Diol Iodophenyl Derivative; (1R,2R)-4-Iodo-α,β-dihydroxy-β-aminopropylbenzene; (1R,2R)-β-Amino-α,γ-dihydroxy-4-iodohydrocinnamyl alcohol; AR-2A1IPD; Contact for additional synonyms.
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Quality Control

Our (1R,2R)-2-Amino-1-(4-Iodophenyl)Propane-1,3-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Chiral Purity (Chiral HPLC) ≥ 99.0% ee
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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