Description

L-2-(5-Chlorothienyl)Alanine is a non-natural, chiral amino acid derivative featuring a chlorinated thiophene side chain, serving as a critical building block in advanced organic synthesis. Its unique structure makes it an essential precursor for the development of novel pharmaceuticals, particularly in the creation of peptide-based therapeutics and enzyme inhibitors. This high-purity intermediate is primarily sought by research institutions and pharmaceutical companies engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially protease inhibitors and receptor antagonists.
• Peptide Chemistry: Incorporation into custom peptides to modulate biological activity, stability, and binding affinity for therapeutic applications.
• Chemical Biology Probes: Used in the synthesis of labeled compounds and molecular probes for studying enzyme mechanisms and biological pathways.
• Asymmetric Synthesis: Serves as a valuable starting material or chiral auxiliary in stereoselective catalytic reactions.
• Agrochemical Research: Potential building block for the synthesis of novel compounds with herbicidal or insecticidal activity.
• Material Science: Exploration into functionalized monomers for specialty polymers with unique electronic or optical properties.

Basic Information

Product Name	L-2-(5-Chlorothienyl)Alanine
CAS No.	911471-88-0
Molecular Formula	C7H8ClNO2S
Molecular Weight	205.66 g/mol
Synonyms	(S)-2-Amino-3-(5-chlorothiophen-2-yl)propanoic acid; L-5-Chlorothien-2-ylalanine; L-β-(5-Chloro-2-thienyl)alanine; 2-Thiophenepropanoic acid, α-amino-5-chloro-, (αS)-; 911471-88-0; L-2-(5-Chlorothienyl)Alanine; (S)-3-(5-Chlorothiophen-2-yl)-2-aminopropanoic acid; 5-Chloro-2-thienyl-L-alanine
EINECS	Contact for details

Quality Control

Our L-2-(5-Chlorothienyl)Alanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.