Description

Alanine,3-[4-(p-Hydroxyphenoxy)-3-Iodophenyl]-,Hydrochloride is a specialized iodinated aromatic amino acid derivative, designed for advanced research and pharmaceutical development. This compound is of significant interest for its potential as a key synthetic intermediate or a molecular scaffold in the creation of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for projects involving thyroid hormone analogs, enzyme inhibitors, or targeted radiopharmaceuticals. The hydrochloride salt form enhances its stability and solubility for precise laboratory handling.

Application

• Medicinal Chemistry Research: Serves as a crucial building block for the synthesis of novel drug candidates, especially those targeting hormone receptors or requiring iodine for molecular recognition.
• Pharmaceutical Intermediates: Used in the multi-step synthesis of complex active pharmaceutical ingredients (APIs) with specific structural motifs.
• Biochemical Probes: Acts as a precursor for labeled compounds in biochemical assays and mechanism-of-action studies.
• Radiopharmaceutical Development: The iodine atom provides a potential site for radioisotope labeling (e.g., I-125, I-131) for diagnostic imaging or therapeutic applications.
• Organic Synthesis Reference Standard: Employed as a high-purity standard for analytical method development and validation in quality control laboratories.

Basic Information

Item	Details
Product Name	Alanine,3-[4-(p-Hydroxyphenoxy)-3-Iodophenyl]-,Hydrochloride
CAS No.	911446-84-9
Molecular Formula	C15H14INO4 • HCl
Molecular Weight	435.64 g/mol (Free base: 399.18 g/mol)
Synonyms	3-[4-(4-Hydroxyphenoxy)-3-iodophenyl]alanine hydrochloride; (2S)-2-Amino-3-[4-(4-hydroxyphenoxy)-3-iodophenyl]propanoic acid hydrochloride; L-Alanine, 3-[4-(p-hydroxyphenoxy)-3-iodophenyl]-, hydrochloride; 3-(4-(4-Hydroxyphenoxy)-3-iodophenyl)-L-alanine HCl; p-Hydroxyphenoxy-3-iodophenylalanine hydrochloride
EINECS	Contact for details

Quality Control

Our Alanine,3-[4-(p-Hydroxyphenoxy)-3-Iodophenyl]-,Hydrochloride is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.