Description

1H-Indazole-1-Carboxylic Acid, 5-[[2-[3-(Acetyloxy)Phenyl]-4-Quinazolinyl]Amino]-, 1,1-Dimethylethyl Ester is a sophisticated heterocyclic organic compound featuring a complex molecular architecture that combines indazole, quinazoline, and ester functionalities. This compound matters as a key advanced intermediate in the synthesis of targeted pharmaceutical agents, particularly in oncology and kinase inhibitor research. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic candidates.

Application

This high-purity intermediate is designed for critical research and development applications, including:

• Pharmaceutical Intermediate: Serving as a key building block in the synthesis of novel drug candidates, particularly kinase inhibitors.
• Oncology Research: Utilized in the development of targeted cancer therapies due to its specific quinazoline-based structure.
• Biochemical Tool Compound: Used in assay development and target validation studies within academic and industrial research settings.
• Process Chemistry: Employed in route scouting and scale-up studies for Active Pharmaceutical Ingredient (API) manufacturing.
• Custom Synthesis: A starting material for the preparation of more complex, functionalized molecules for biological screening.

Basic Information

Product Name	1H-Indazole-1-Carboxylic Acid, 5-[[2-[3-(Acetyloxy)Phenyl]-4-Quinazolinyl]Amino]-, 1,1-Dimethylethyl Ester
CAS No.	911417-25-9
Molecular Formula	C30H27N5O4
Molecular Weight	521.57 g/mol
Synonyms	tert-Butyl 5-((2-(3-acetoxyphenyl)quinazolin-4-yl)amino)-1H-indazole-1-carboxylate; 5-[[2-[3-(Acetyloxy)Phenyl]-4-Quinazolinyl]Amino]-1H-indazole-1-carboxylic Acid 1,1-Dimethylethyl Ester; 1-(tert-Butoxycarbonyl)-5-((2-(3-acetoxyphenyl)quinazolin-4-yl)amino)-1H-indazole; BOC-protected Indazole-Quinazoline Amine Ester; 911417-25-9; Advanced Quinazoline-Indazole Hybrid Intermediate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing HPLC purity, NMR confirmation, and other critical parameters are provided with each shipment. We support development under cGMP guidelines where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.