Description

(Sr,2R,3S)-2-(o-Boc)-3-(tert-Butylsulfinyl)-3-Phenylisoserine Methyl Ester is a high-purity, chiral building block of significant importance in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with defined stereochemistry, which is critical for pharmaceutical efficacy. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of complex drug candidates, particularly those requiring high stereochemical purity.
• Peptidomimetic Research: Used in the construction of non-peptide scaffolds that mimic peptide structure and function for drug discovery.
• Asymmetric Synthesis: Serves as a starting material or intermediate in catalytic and stoichiometric asymmetric transformations to introduce chiral centers.
• API Development: Employed in the research and process development stages for new Active Pharmaceutical Ingredients, especially in oncology and antiviral therapeutic areas.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for CDMOs (Contract Development and Manufacturing Organizations) specializing in producing bespoke, high-value intermediates for clients.
• Academic & Industrial R&D: Utilized in research laboratories for methodological studies in organic chemistry and the development of new synthetic routes.

Basic Information

Product Name	(Sr,2R,3S)-2-(o-Boc)-3-(tert-Butylsulfinyl)-3-Phenylisoserine Methyl Ester
CAS No.	911199-16-1
Molecular Formula	C20H31NO6S
Molecular Weight	413.53 g/mol
Synonyms	(Sr,2R,3S)-2-[(tert-Butoxycarbonyl)oxy]-3-[(R)-tert-Butylsulfinyl]-3-phenyl-2-methylpropanoate; Methyl (2R,3S)-3-[(R)-tert-Butylsulfinyl]-2-hydroxy-3-phenylpropionate N-Boc Derivative; (Sr,2R,3S)-2-(Boc-oxy)-3-((R)-tert-Butylsulfinyl)-3-phenylisoserine Methyl Ester; Boc-Protected tert-Butylsulfinyl Phenylisoserine Methyl Ester; Chiral Sulfinyl Ester Intermediate 911199-16-1; N-Boc-O-Methyl-3-phenyl-3-((R)-tert-butylsulfinyl)isoserine
EINECS	Contact for details

Quality Control

Every batch of (Sr,2R,3S)-2-(o-Boc)-3-(tert-Butylsulfinyl)-3-Phenylisoserine Methyl Ester is produced and controlled under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure high chemical and stereochemical purity, meeting the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.