Description

(Sr,2R,3S)-2-(o-Boc)-3-(tert-Butylsulfinyl)-3-Phenylisoserine Benzyl Ester is a sophisticated chiral building block of significant importance in modern asymmetric synthesis. This compound is valued for its role as a key intermediate in the production of complex pharmaceutical molecules, particularly taxane derivatives and other bioactive compounds. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of complex drug candidates, including anticancer agents.
• Asymmetric Synthesis: Utilized in stereoselective reactions to construct molecules with high enantiomeric purity for medicinal chemistry research.
• API Development: Serves as a key precursor in the research and process development of new Active Pharmaceutical Ingredients (APIs).
• Fine Chemical Production: Employed in the manufacture of high-value, specialty chemicals requiring precise stereochemical control.
• Academic & Industrial Research: Used in laboratories for methodological development in organic and organometallic chemistry.
• Process Chemistry: Investigated for scalable synthetic routes in pilot plants and commercial manufacturing settings.

Basic Information

Product Name	(Sr,2R,3S)-2-(o-Boc)-3-(tert-Butylsulfinyl)-3-Phenylisoserine Benzyl Ester
CAS No.	911199-15-0
Molecular Formula	C25H31NO6S
Molecular Weight	473.58 g/mol
Synonyms	(2R,3S)-3-[(R)-tert-Butylsulfinyl]-2-[(tert-Butoxycarbonyl)amino]-3-phenylpropanoic Acid Benzyl Ester; Benzyl (2R,3S)-3-[(R)-tert-Butylsulfinyl]-2-[(tert-butoxycarbonyl)amino]-3-phenylpropanoate; (2R,3S)-N-Boc-3-[(R)-tert-Butylsulfinyl]-3-phenylisoserine Benzyl Ester; (Sr,2R,3S)-2-(o-Boc)-3-(tert-Butylsulfinyl)-3-Phenylisoserine Bn Ester; Taxol Side Chain Intermediate; Chiral Sulfinimide Ester; β-Amino Ester Building Block.
EINECS	Contact for details

Quality Control

Our (Sr,2R,3S)-2-(o-Boc)-3-(tert-Butylsulfinyl)-3-Phenylisoserine Benzyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including chiral HPLC and NMR, to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with cGMP and other relevant pharmaceutical guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.