Description

4-(4-Fluorophenyl)-7-[[[5-[(1S)-1-Hydroxy-1-(Trifluoromethyl)Propyl]-1,3,4-Oxadiazol-2-Yl]Amino]Methyl]-2H-1-Benzopyran-2-One is a high-purity, non-racemic chiral compound featuring a complex molecular architecture that combines a coumarin core with fluorinated and heterocyclic motifs. This compound is of significant interest for its potential as a key pharmaceutical intermediate or advanced research chemical in drug discovery programs. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Probe Development: Potential utility in designing fluorescent or activity-based probes for studying biological processes due to its coumarin fluorophore.
• Organic Synthesis Reference Standard: Provides a high-purity standard for analytical method development and validation in synthetic chemistry.
• Academic & Institutional Research: Supports cutting-edge chemical and pharmacological research in universities and government institutes.

Basic Information

Product Name	4-(4-Fluorophenyl)-7-[[[5-[(1S)-1-Hydroxy-1-(Trifluoromethyl)Propyl]-1,3,4-Oxadiazol-2-Yl]Amino]Methyl]-2H-1-Benzopyran-2-One
CAS No.	910656-27-8
Molecular Formula	C22H17F4N3O4
Molecular Weight	463.38 g/mol
Synonyms	4-(4-Fluorophenyl)-7-({[5-((1S)-1-Hydroxy-1-trifluoromethylpropyl)-1,3,4-oxadiazol-2-yl]amino}methyl)-2H-chromen-2-one; (S)-4-(4-Fluorophenyl)-7-((5-(1-hydroxy-1-(trifluoromethyl)propyl)-1,3,4-oxadiazol-2-ylamino)methyl)-2H-chromen-2-one; 910656-27-8; Fluorinated Coumarin-Oxadiazole Hybrid; Chiral Oxadiazole-Coumarin Derivative; CAS 910656-27-8
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and chiral integrity. Certificates of Analysis (COA) are provided with each shipment, detailing results from HPLC, NMR, and chiral purity analysis. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.