Description

(3R)-n-(tert-Butyloxycarbonyl)-3-Methyl-L-Glutamic Acid CAS NO 910548-26-4 is a high-purity, protected amino acid derivative essential for advanced peptide synthesis and pharmaceutical research. This compound serves as a critical chiral building block, enabling the precise construction of complex molecules with defined stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies developing novel therapeutic peptides and active pharmaceutical ingredients (APIs).

Application

• Peptide Synthesis: A key chiral intermediate for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics.
• Pharmaceutical Research: Used in the discovery and development of new drug candidates, particularly in oncology, metabolic disorders, and neurology.
• API Manufacturing: Serves as a building block in the production of Active Pharmaceutical Ingredients (APIs) requiring specific stereochemical configurations.
• Bioconjugation: Employed in the design of antibody-drug conjugates (ADCs) and other targeted drug delivery systems.
• Chemical Biology: A valuable tool for probing enzyme mechanisms and studying protein-protein interactions.
• Process Chemistry: Used in the development and scale-up of synthetic routes for complex organic molecules.

Basic Information

Product Name	(3R)-n-(tert-Butyloxycarbonyl)-3-Methyl-L-Glutamic Acid
CAS No.	910548-26-4
Molecular Formula	C11H19NO6
Molecular Weight	261.27 g/mol
Synonyms	Boc-3-Me-L-Glu-OH; (3R)-3-Methyl-N-[(2-methylpropan-2-yl)oxycarbonyl]-L-glutamic acid; (3R)-3-Methyl-N-(tert-butoxycarbonyl)-L-glutamic acid; Boc-(3R)-3-methyl-L-glutamic acid; (3R)-N-Boc-3-methyl-L-glutamic acid; tert-Butyl (3R)-3-methyl-1,5-dioxo-1,5-bis(oxidanyl)pentan-2-ylcarbamate; 910548-26-4
EINECS	Contact for details

Quality Control

Our (3R)-n-(tert-Butyloxycarbonyl)-3-Methyl-L-Glutamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive identification tests. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.