Description

(2S,3R)-3-Methylglutamic Acid Hydrochloride Salt is a high-purity, stereochemically defined amino acid derivative. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, offering precise control over molecular architecture. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and metabolic probes.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, including enzyme inhibitors and receptor modulators.
• Peptide Chemistry: Used in the solid-phase and solution-phase synthesis of modified peptides to study structure-activity relationships (SAR).
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and metabolic pathway analysis.
• Asymmetric Synthesis: Serves as a starting material or auxiliary for constructing complex molecules with defined stereocenters.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(2S,3R)-3-Methylglutamic Acid Hydrochloride Salt
CAS No.	910548-20-8
Molecular Formula	C6H11NO4 • HCl
Molecular Weight	197.62 g/mol (Free base: 161.16)
Synonyms	(2S,3R)-3-Methyl-L-glutamic Acid Hydrochloride; (2S,3R)-3-Methylglutamic Acid HCl; 3-Methyl-DL-glutamic Acid Hydrochloride (mixed isomers); (3R)-3-Methyl-L-glutamic Acid Hydrochloride; 3-Methylglutamic Acid Hydrochloride Salt; H-3-Me-Glu-OH • HCl; 2-Amino-3-methylpentanedioic Acid Hydrochloride
EINECS	Contact for details

Quality Control

Our (2S,3R)-3-Methylglutamic Acid Hydrochloride Salt is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, potency, and purity meet stringent specifications. Certificates of Analysis (COA) detailing all test results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% de (2S,3R)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.