Description

3-Isoquinolinecarboxamide, n-[(1S)-2-[4-[4-(Hydroxyamino)-4-Oxobutyl]-1-Piperidinyl]-1-(Hydroxymethyl)-2-Oxoethyl]- is a high-purity, synthetically derived small molecule with a complex heterocyclic structure. This compound is of significant interest in advanced pharmaceutical research and development, particularly as a key intermediate or active pharmaceutical ingredient (API) precursor for novel therapeutics. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of targeted drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in oncology and targeted therapy research.
• HDAC Inhibitor Research: Used in the development and study of histone deacetylase (HDAC) inhibitors, a promising class of epigenetic regulators for cancer treatment.
• Biochemical Tool Compound: Employed in vitro and in vivo studies to investigate specific biological pathways and enzyme interactions.
• Preclinical Development: Supplied to support early-stage drug discovery, lead optimization, and preclinical testing phases.
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Custom Synthesis Starting Material: Used by fine chemical suppliers for the tailored synthesis of more complex, customer-specific molecular entities.

Basic Information

Product Name	3-Isoquinolinecarboxamide, n-[(1S)-2-[4-[4-(Hydroxyamino)-4-Oxobutyl]-1-Piperidinyl]-1-(Hydroxymethyl)-2-Oxoethyl]-
CAS No.	910538-99-7
Molecular Formula	C22H30N4O6
Molecular Weight	446.50 g/mol
Synonyms	N-[(2S)-1-Hydroxy-3-[4-[4-(hydroxyamino)-4-oxobutyl]piperidin-1-yl]-1-oxopropan-2-yl]isoquinoline-3-carboxamide; (S)-2-(4-(4-(Hydroxyamino)-4-oxobutyl)piperidin-1-yl)-1-(hydroxymethyl)-2-oxoethyl)isoquinoline-3-carboxamide; UNII-2P6Q4MM462; 2P6Q4MM462; CHEMBL3186662; A chemical intermediate for HDAC inhibitors; A potential API precursor.
EINECS	Contact for details

Quality Control

Our 3-Isoquinolinecarboxamide derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.