Description

2-Aminomethyl-3-(4-Trifluoromethyl-Phenyl)-Propionic Acid is a specialized, high-value pharmaceutical intermediate characterized by its unique trifluoromethylphenyl and aminomethyl propionic acid structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of targeted therapeutics. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry, process development, and the production of advanced drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, especially those targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up API synthesis from laboratory to pilot and commercial scale.
• Protease Inhibitor Synthesis: Its structural features make it a valuable precursor for compounds designed to inhibit specific enzyme classes.
• Peptidomimetic Development: Incorporated into the design of peptide-like molecules with enhanced stability and bioavailability.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of client-specific advanced intermediates.

Basic Information

Product Name	2-Aminomethyl-3-(4-Trifluoromethyl-Phenyl)-Propionic Acid
CAS No.	910443-97-9
Molecular Formula	C11H12F3NO2
Molecular Weight	247.21 g/mol
Synonyms	2-(Aminomethyl)-3-[4-(trifluoromethyl)phenyl]propanoic acid; 3-(4-Trifluoromethylphenyl)-2-aminomethylpropionic acid; 2-Aminomethyl-3-(4-trifluoromethylphenyl)propanoic acid; α-(Aminomethyl)-4-(trifluoromethyl)benzenepropanoic acid; 910443-97-9; (4-Trifluoromethylphenyl)-2-aminomethylpropionic acid
EINECS	Contact for details

Quality Control

Our production of 2-Aminomethyl-3-(4-Trifluoromethyl-Phenyl)-Propionic Acid adheres to stringent quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the exacting standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with full traceability are provided for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.