Description

2-Aminomethyl-3-(4-Bromo-Phenyl)-Propionic Acid is a specialized brominated phenylalanine derivative that serves as a critical chiral building block in advanced organic synthesis. Its unique structure, featuring both an amino acid backbone and a halogenated aromatic ring, makes it a valuable precursor for constructing complex molecules with high stereochemical control. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptidomimetics, and other fine chemicals where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) targets and enzyme inhibitors.
• Peptidomimetic Chemistry: Used to incorporate non-natural amino acid residues into peptide chains to enhance stability, bioavailability, and biological activity.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Employed in the synthesis of novel crop protection agents and herbicides due to its halogenated aromatic system.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists exploring new reaction methodologies and constructing complex molecular libraries.

Basic Information

Product Name	2-Aminomethyl-3-(4-Bromo-Phenyl)-Propionic Acid
CAS No.	910443-87-7
Molecular Formula	C11H12BrNO2
Molecular Weight	270.12 g/mol
Synonyms	2-(Aminomethyl)-3-(4-bromophenyl)propanoic acid; 3-(4-Bromophenyl)-2-(aminomethyl)propanoic acid; (2R/S)-2-(Aminomethyl)-3-(4-bromophenyl)propionic acid; 4-Bromo-β-homophenylalanine; β-Homo-4-bromophenylalanine; 2-Aminomethyl-3-(p-bromophenyl)propionic acid; DL-2-Aminomethyl-3-(4-bromophenyl)propionic acid
EINECS	Contact for details

Quality Control

Our production of 2-Aminomethyl-3-(4-Bromo-Phenyl)-Propionic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic (HPLC, GC) and spectroscopic (NMR, IR, MS) techniques to confirm identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (where applicable), residual solvents, and heavy metals is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.