Description

2-Aminomethyl-3-(4-Fluoro-Phenyl)-Propionic Acid is a specialized fluorinated amino acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and a carboxylic acid functional group on a fluorinated phenylpropionic acid backbone, makes it a valuable intermediate for creating complex molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapies.
• Peptidomimetic Chemistry: Used to incorporate non-natural amino acid residues into peptide chains to enhance stability, bioavailability, and binding affinity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Research: Employed in the synthesis of novel herbicides and pesticides that leverage the fluorine atom for improved efficacy and environmental profile.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers and advanced materials with specific functional properties.

Basic Information

Product Name	2-Aminomethyl-3-(4-Fluoro-Phenyl)-Propionic Acid
CAS No.	910443-83-3
Molecular Formula	C11H14FNO2
Molecular Weight	211.23 g/mol
Synonyms	3-(4-Fluorophenyl)-2-(aminomethyl)propanoic acid; 2-(Aminomethyl)-3-(4-fluorophenyl)propanoic acid; β-(4-Fluorophenyl)-β-alanine, 2-aminoethyl derivative; (RS)-2-Aminomethyl-3-(4-fluorophenyl)propionic acid; DL-2-Aminomethyl-3-(4-fluorophenyl)propionic acid; 4-Fluoro-DL-homophenylalanine, 2-aminoethyl-; Fmoc-4-Fluoro-hPhe(2-Aminoethyl)-OH (precursor form); 910443-83-3
EINECS	Contact for details

Quality Control

Every batch of 2-Aminomethyl-3-(4-Fluoro-Phenyl)-Propionic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.