Description

3-(Azetidin-3-Yl)Cyclohexanecarboxylic Acid is a versatile bifunctional organic compound featuring both an azetidine ring and a carboxylic acid group on a cyclohexane scaffold. This unique structure makes it a valuable pharmacophore and key building block in modern synthetic chemistry, particularly for constructing complex molecules with specific three-dimensional geometries. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Medicinal Chemistry Building Block: Used to introduce the constrained azetidine moiety and carboxylic acid functionality, enabling structure-activity relationship (SAR) studies and molecular optimization.
• Peptidomimetic Research: Serves as a scaffold for designing peptide mimics and protease inhibitors due to its rigid, alicyclic structure.
• Ligand Synthesis for Catalysis: Employed in the development of chiral ligands and organocatalysts for asymmetric synthesis.
• Agrochemical Research: Potential intermediate in the creation of new herbicides or fungicides with novel modes of action.
• Material Science: Can be utilized as a monomer or cross-linking agent for specialty polymers with tailored properties.

Basic Information

Product Name	3-(Azetidin-3-Yl)Cyclohexanecarboxylic Acid
CAS No.	910442-39-6
Molecular Formula	C10H17NO2
Molecular Weight	183.25 g/mol
Synonyms	3-(Azetidin-3-yl)cyclohexanecarboxylic acid; Cyclohexanecarboxylic acid, 3-(3-azetidinyl)-; 3-Azetidin-3-ylcyclohexanecarboxylic acid; 3-(Azetidin-3-yl)cyclohexane-1-carboxylic acid; (1r,3r)-3-(Azetidin-3-yl)cyclohexanecarboxylic acid; (1s,3s)-3-(Azetidin-3-yl)cyclohexanecarboxylic acid; AZ-3-CHCA; 910442-39-6
EINECS	Contact for details

Quality Control

Our 3-(Azetidin-3-Yl)Cyclohexanecarboxylic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (NMR, IR, MS), to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with full analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.