Description

[2-(3-Bromophenyl)-2-Hydroxyethyl]-Carbamic Acid 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific brominated aromatic structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical manufacturers and contract research organizations (CROs) focused on developing new therapeutic agents, particularly in areas requiring complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop molecules with improved efficacy and safety profiles.
• API Synthesis: Serves as a crucial building block in multi-step synthetic routes for the production of complex, target-specific active pharmaceutical ingredients.
• Chemical Biology Probes: Employed in the development of chemical probes for studying biological pathways and protein functions in academic and industrial research settings.
• Process Development & Scale-Up: Used by process chemists to develop robust, scalable, and cost-effective manufacturing routes for promising drug candidates.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) specializing in the custom synthesis of complex organic molecules for client-specific projects.

Basic Information

Product Name	[2-(3-Bromophenyl)-2-Hydroxyethyl]-Carbamic Acid 1,1-Dimethylethyl Ester
CAS No.	910309-46-5
Molecular Formula	C13H18BrNO3
Molecular Weight	316.19 g/mol
Synonyms	tert-Butyl N-[2-(3-bromophenyl)-2-hydroxyethyl]carbamate; 2-(3-Bromophenyl)-2-hydroxyethyl carbamic acid tert-butyl ester; N-Boc-2-amino-1-(3-bromophenyl)ethanol; 1-(3-Bromophenyl)-2-[(tert-butoxycarbonyl)amino]ethanol; Boc-3-Br-Phe-ol; (2R/S)-2-[(tert-Butoxycarbonyl)amino]-2-(3-bromophenyl)ethanol; N-(tert-Butoxycarbonyl)-2-amino-2-(3-bromophenyl)ethanol
EINECS	Contact for details

Quality Control

Our [2-(3-Bromophenyl)-2-Hydroxyethyl]-Carbamic Acid 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development, ensuring reliability for your critical research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.