Description

1,5-Cyclopregn-4-Ene-2,20-Dione, 11,21-Dihydroxy-16,17-[(1-Methylethylidene)Bis(Oxy)]-, (1β,5R,11β,16α)- (9Ci) is a high-purity synthetic steroid derivative with a complex, multi-functional molecular structure. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors seeking to develop new steroid-based medications.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel corticosteroid analogs and other potent steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry programs to study structure-activity relationships (SAR) and develop new therapeutic candidates targeting inflammation, immune response, and hormonal pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Process Chemistry: Employed in scaling up synthetic routes for the production of specialty steroids under controlled GMP or non-GMP conditions.
• Biochemical Research: Utilized in studies investigating steroid receptor binding, enzyme inhibition, and metabolic pathways.

Basic Information

Product Name	1,5-Cyclopregn-4-Ene-2,20-Dione, 11,21-Dihydroxy-16,17-[(1-Methylethylidene)Bis(Oxy)]-, (1β,5R,11β,16α)- (9Ci)
CAS No.	910299-72-8
Molecular Formula	C24H32O6
Molecular Weight	416.51 g/mol
Synonyms	16α,17α-Isopropylidenedioxy-11β,21-dihydroxy-1,5-cyclopregn-4-ene-2,20-dione; (1β,5R,11β,16α)-11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-1,5-cyclopregn-4-ene-2,20-dione; 1,5-Cyclopregn-4-ene-2,20-dione, 11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (1β,5R,11β,16α)-; Steroid Intermediate 910299-72-8; 16α,17α-Acetonide derivative of a 1,5-cyclopregnane dione.
EINECS	Contact for details

Quality Control

Our 1,5-Cyclopregn-4-Ene-2,20-Dione derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.