Description

Potassium tert-Butoxymethyltrifluoroborate is a specialized organoboron reagent, a potassium trifluoroborate salt, valued for its enhanced stability and handling properties compared to traditional boronic acids. This compound serves as a crucial coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex molecules. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing carbon-carbon bonds under mild conditions.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing biaryl and alkyl-aryl linkages in active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Development: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific aryl motifs.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and semiconductors.
• Cross-Coupling Reactions: Specifically designed as a stable, air-tolerant reagent for robust Suzuki-Miyaura cross-coupling, often offering superior performance in challenging couplings.
• Chemical Biology & Probe Development: Useful for incorporating boron-containing tags or modifying biomolecules for sensing and diagnostic applications.
• Process Chemistry & Scale-Up: Its improved stability makes it suitable for optimizing and scaling synthetic routes from laboratory to pilot plant scale.

Basic Information

Product Name	Potassium tert-Butoxymethyltrifluoroborate
CAS No.	910251-10-4
Molecular Formula	C5H11BF3KO
Molecular Weight	194.05 g/mol
Synonyms	Potassium (tert-Butoxymethyl)trifluoroborate; Potassium Trifluoro(tert-butoxymethyl)borate; tert-Butoxymethyltrifluoroborate Potassium Salt; (tert-Butoxymethyl)potassium Trifluoroborane; Methyl(tert-butoxy)potassium Trifluoroborate; KTFB-tBuOMe; Potassium (tert-Butyloxymethyl)trifluoroboranuide
EINECS	Contact for details

Quality Control

Our Potassium tert-Butoxymethyltrifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 13C) and HPLC analysis, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) to maintain stability and prevent decomposition. Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
11B NMR Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.