Description

4-Methyl-3,4-Dihydro-2H-Pyrido[3,2-B][1,4]Oxazine-7-Sulfonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive sulfonyl chloride functional group. This compound matters for its critical role as a key building block in the synthesis of complex, biologically active molecules, enabling the formation of sulfonamide linkages. It is primarily needed by research and development teams and process chemists in the pharmaceutical and agrochemical industries for the creation of novel drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing sulfonamide pharmacophores.
• Drug Discovery & Medicinal Chemistry: Used in research laboratories for the design and development of new chemical entities targeting various therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor in the manufacturing of advanced crop protection agents and herbicides.
• Chemical Biology Probes: Employed in the development of molecular probes and inhibitors for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and commercial production.
• Sulfonamide Library Synthesis: Facilitates the rapid generation of diverse sulfonamide-based compound libraries for high-throughput screening.

Basic Information

Product Name	4-Methyl-3,4-Dihydro-2H-Pyrido[3,2-B][1,4]Oxazine-7-Sulfonyl Chloride
CAS No.	910037-13-7
Molecular Formula	C9H9ClN2O3S
Molecular Weight	260.70 g/mol
Synonyms	4-Methyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine-7-sulfonyl chloride; 2H-Pyrido[3,2-b][1,4]oxazine-7-sulfonyl chloride, 3,4-dihydro-4-methyl-; 4-Methyl-2H,3H,4H-pyrido[3,2-b][1,4]oxazine-7-sulfonyl chloride; 910037-13-7; 4-Methyl-3,4-dihydro-2H-pyrido[3,2-b]-1,4-oxazine-7-sulfonyl chloride; 4-Methyl-3,4-dihydro-2H-pyrido[3,2-b]oxazine-7-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Methyl-3,4-Dihydro-2H-Pyrido[3,2-B][1,4]Oxazine-7-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.