Description

(R)-3-Amino-3-(3,4-Dichloro-Phenyl)-Propionic Acid is a high-purity, single-enantiomer chiral building block of significant importance in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex, biologically active molecules with defined stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Asymmetric Catalysis Research: Serves as a valuable ligand precursor or substrate in the development of new asymmetric synthetic methodologies.
• Peptidomimetics Development: Incorporated into the design of peptide analogs and mimetics for drug discovery programs targeting protein-protein interactions.
• Reference Standard: Utilized as an analytical standard for quality control and method development in regulatory and analytical laboratories.
• Custom Synthesis Building Block: Employed by fine chemical manufacturers for the contract synthesis of complex, customer-specific target molecules.

Basic Information

Product Name	(R)-3-Amino-3-(3,4-Dichloro-Phenyl)-Propionic Acid
CAS No.	909709-44-0
Molecular Formula	C9H9Cl2NO2
Molecular Weight	234.08 g/mol
Synonyms	(R)-3-Amino-3-(3,4-dichlorophenyl)propanoic acid; (R)-3-Amino-3-(3,4-dichlorophenyl)propionic acid; (3R)-3-Amino-3-(3,4-dichlorophenyl)propanoic acid; (R)-3,4-Dichloro-β-phenyl-β-alanine; (R)-β-Amino-3,4-dichlorohydrocinnamic acid; (R)-3-(3,4-Dichlorophenyl)-3-aminopropionic acid; (R)-Dichlorophenylalanine derivative
EINECS	Contact for details

Quality Control

Our (R)-3-Amino-3-(3,4-Dichloro-Phenyl)-Propionic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is subjected to comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR, and mass spectrometry for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.