Description

n-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Yl)-3,4-Dihydroisoquinoline-2(1H)-Carboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial interest for its role in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder pathways. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in innovative drug synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting specific biological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Biochemical Tool Compound: Serves as a reference standard or probe in pharmacological and biochemical assays.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory chemical biology and drug discovery projects.
• Pre-clinical Development: Integral in producing batches for pre-clinical toxicology and pharmacokinetic studies.

Basic Information

Item	Details
Product Name	n-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Yl)-3,4-Dihydroisoquinoline-2(1H)-Carboxamide
CAS No.	909685-18-3
Molecular Formula	C22H23F3N4O
Molecular Weight	416.44 g/mol
Synonyms	N-[1-[[6-(Trifluoromethyl)-3-pyridinyl]methyl]-4-piperidinyl]-3,4-dihydro-2(1H)-isoquinolinecarboxamide; 1,2,3,4-Tetrahydro-N-[1-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-4-piperidinyl]isoquinoline-2-carboxamide; 909685-18-3; UNII-7V3Q8R5J7F; 7V3Q8R5J7F; CHEMBL3186662; BDBM50157871; AKOS009158950
EINECS	Contact for details

Quality Control

Our n-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Yl)-3,4-Dihydroisoquinoline-2(1H)-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with client specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.