Description

3-[(4-(3-[6-(Trifluoromethyl)Pyridin-3-Yl]-1,2,4-Oxadiazol-5-Yl)Piperidin-1-Yl)Carbonyl]Benzonitrile is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure designed for targeted molecular interactions. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new therapeutic agents, especially within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its unique trifluoromethylpyridine and 1,2,4-oxadiazole motifs.
• Biochemical Tool Compound: Employed in vitro and in vivo to study specific biological pathways and protein-ligand interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Agrochemical Research: Investigated as a precursor for developing new active ingredients with potential herbicidal or insecticidal properties.
• Academic Research: Utilized in university and institutional labs for advanced studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	3-[(4-(3-[6-(Trifluoromethyl)Pyridin-3-Yl]-1,2,4-Oxadiazol-5-Yl)Piperidin-1-Yl)Carbonyl]Benzonitrile
CAS No.	909675-88-3
Molecular Formula	C22H15F3N6O2
Molecular Weight	452.39 g/mol
Synonyms	3-[(4-{3-[6-(Trifluoromethyl)pyridin-3-yl]-1,2,4-oxadiazol-5-yl}piperidin-1-yl)carbonyl]benzonitrile; 3-((4-(3-(6-(Trifluoromethyl)pyridin-3-yl)-1,2,4-oxadiazol-5-yl)piperidine-1-carbonyl)benzonitrile; 909675-88-3; 3-[(4-(3-[6-(Trifluoromethyl)-3-pyridinyl]-1,2,4-oxadiazol-5-yl)-1-piperidinyl]carbonyl]benzonitrile; Benzonitrile, 3-[[4-[3-[6-(trifluoromethyl)-3-pyridinyl]-1,2,4-oxadiazol-5-yl]-1-piperidinyl]carbonyl]-
EINECS	Contact for details

Quality Control

Our production of 3-[(4-(3-[6-(Trifluoromethyl)Pyridin-3-Yl]-1,2,4-Oxadiazol-5-Yl)Piperidin-1-Yl)Carbonyl]Benzonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity suitable for advanced research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We implement in-process controls and final release testing aligned with ICH guidelines for impurities to meet the exacting standards of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.