Description

1-(4-Fluorobenzyl)-4-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Yl)Piperazine is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure with fluorine and trifluoromethyl substituents. This compound is critical for medicinal chemistry research and development, offering a sophisticated scaffold for modulating the biological activity and pharmacokinetic properties of new drug candidates. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a core scaffold in structure-activity relationship (SAR) studies to optimize potency, selectivity, and metabolic stability of drug candidates.
• Process Chemistry Development: Employed in route scouting and scale-up optimization for the efficient and cost-effective production of developmental drugs.
• Biochemical Tool Compound: May be utilized in vitro to probe specific biological pathways or protein targets due to its distinctive chemical structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development programs for global clients.

Basic Information

Product Name	1-(4-Fluorobenzyl)-4-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Yl)Piperazine
CAS No.	909670-69-5
Molecular Formula	C23H26F4N4
Molecular Weight	434.48 g/mol
Synonyms	4-[1-({6-[(Trifluoromethyl)pyridin-3-yl]}methyl)piperidin-4-yl]-1-[(4-fluorophenyl)methyl]piperazine; 1-[(4-Fluorophenyl)methyl]-4-[1-({6-[(trifluoromethyl)pyridin-3-yl]}methyl)piperidin-4-yl]piperazine; 909670-69-5; UNII-4Q8K6F8Q5K; 4Q8K6F8Q5K; BDBM50380785; AKOS025147424; ZINC000103074511
EINECS	Contact for details

Quality Control

Every batch of 1-(4-Fluorobenzyl)-4-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Yl)Piperazine is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the exacting standards of pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is sensitive to strong alkali and should be stored separately from incompatible materials. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.