Description

3-[(4-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperazin-1-Yl)Methyl]-2H-1,2,4-Benzothiadiazine 1,1-Dioxide is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates for various disease targets.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new chemical entities (NCEs) for drug discovery programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties of lead compounds.
• API Development: Serves as a precursor in the development and scale-up of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) or metabolic disorders.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for pharmacological studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	3-[(4-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperazin-1-Yl)Methyl]-2H-1,2,4-Benzothiadiazine 1,1-Dioxide
CAS No.	909667-70-5
Molecular Formula	C21H21F3N6O2S
Molecular Weight	478.49 g/mol
Synonyms	3-[(4-{[6-(Trifluoromethyl)pyridin-3-yl]methyl}piperazin-1-yl)methyl]-4H-1,2,4-benzothiadiazine 1,1-dioxide; 3-[(4-{[6-(Trifluoromethyl)-3-pyridinyl]methyl}-1-piperazinyl)methyl]-2H-1,2,4-benzothiadiazine 1,1-dioxide; 3-((4-((6-(Trifluoromethyl)pyridin-3-yl)methyl)piperazin-1-yl)methyl)-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide; 909667-70-5; UNII-6G2J7Q9Q4N
EINECS	Contact for details

Quality Control

Our 3-[(4-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperazin-1-Yl)Methyl]-2H-1,2,4-Benzothiadiazine 1,1-Dioxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.