Description

1-(2,6-Dimethoxybenzyl)-n-Methyl-n-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Amine is a high-value, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system and other therapeutic areas. It is primarily sought by pharmaceutical R&D laboratories, custom synthesis providers, and agrochemical innovators for its role as a key building block in drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Agrochemical Active Ingredient Synthesis: Serves as a precursor in the development of advanced crop protection agents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.
• Biochemical Tool Compound: Utilized in pharmacological assays and as a reference standard in analytical method development.
• Academic & Institutional Research: Employed in university and research institute laboratories for exploratory synthetic chemistry projects.

Basic Information

Product Name	1-(2,6-Dimethoxybenzyl)-n-Methyl-n-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Amine
CAS No.	909666-52-0
Molecular Formula	C22H28F3N3O2
Molecular Weight	423.47 g/mol
Synonyms	1-[(2,6-Dimethoxyphenyl)methyl]-N-methyl-N-{[6-(trifluoromethyl)pyridin-3-yl]methyl}piperidin-4-amine; 4-Amino-1-[(2,6-dimethoxyphenyl)methyl]-N-methyl-N-{[6-(trifluoromethyl)pyridin-3-yl]methyl}piperidine; 909666-52-0; UNII-7K3K8Q9Z4V; 7K3K8Q9Z4V; CHEMBL3186472; BDBM50389351; AKOS009158492
EINECS	Contact for details

Quality Control

Our production of 1-(2,6-Dimethoxybenzyl)-n-Methyl-n-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)Piperidin-4-Amine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support custom synthesis under cGMP guidelines for advanced development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.