Description

n-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Carbonyl)Piperidin-4-Yl)Indoline-1-Carboxamide is a sophisticated heterocyclic organic compound featuring a trifluoromethylpyridine core, a piperidine linker, and an indoline carboxamide moiety, making it a valuable intermediate in advanced chemical synthesis. This compound is critical for research and development in the pharmaceutical sector, where its unique structure serves as a key building block for creating novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories, agrochemical research units, and specialty chemical manufacturers focused on developing new therapeutic agents and high-performance materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the biological activity of the trifluoromethylpyridine group.
• Chemical Biology Probe: Acts as a scaffold or ligand in the design of molecular probes for studying enzyme inhibition and receptor binding mechanisms.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with specific thermal or optical properties.
• Contract Research & Development (CRO/CMO): Supplied to outsourcing partners for custom synthesis projects and process optimization.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	n-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Carbonyl)Piperidin-4-Yl)Indoline-1-Carboxamide
CAS No.	909661-27-4
Molecular Formula	C21H19F3N4O2
Molecular Weight	416.40 g/mol
Synonyms	1-[(6-(Trifluoromethyl)pyridine-3-carbonyl)piperidin-4-yl]indoline-1-carboxamide; N-[1-[[6-(Trifluoromethyl)-3-pyridinyl]carbonyl]-4-piperidinyl]-2,3-dihydro-1H-indole-1-carboxamide; 909661-27-4; 1H-Indole-1-carboxamide, N-[1-[[6-(trifluoromethyl)-3-pyridinyl]carbonyl]-4-piperidinyl]-2,3-dihydro-; N-(1-((6-(Trifluoromethyl)pyridine-3-carbonyl)piperidin-4-yl)indoline-1-carboxamide
EINECS	Contact for details

Quality Control

Our n-(1-([6-(Trifluoromethyl)Pyridin-3-Yl]Carbonyl)Piperidin-4-Yl)Indoline-1-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.