Description

4-(Pyridin-2-Ylmethyl)-1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)-1,4-Diazepan-5-One is a high-purity, advanced pharmaceutical intermediate featuring a complex diazepanone core structure. This compound is of significant commercial interest due to its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the production of targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis to explore new chemical entities.
• Process Chemistry & Scale-Up: Employed in the development and optimization of robust, scalable synthetic routes for Good Manufacturing Practice (GMP) production.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-(Pyridin-2-Ylmethyl)-1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)-1,4-Diazepan-5-One
CAS No.	909659-43-4
Molecular Formula	C19H19F3N4O
Molecular Weight	376.38 g/mol
Synonyms	1,4-Diazepan-5-one, 4-[(2-pyridinyl)methyl]-1-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-; 4-(Pyridin-2-ylmethyl)-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)-1,4-diazepan-5-one; 5H-1,4-Diazepin-5-one, 4-(2-pyridinylmethyl)-1-[6-(trifluoromethyl)-3-pyridinyl]methyl]-; 909659-43-4; Advanced Diazepanone Intermediate; Trifluoromethylpyridine Diazepanone Derivative
EINECS	Contact for details

Quality Control

Every batch of 4-(Pyridin-2-Ylmethyl)-1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)-1,4-Diazepan-5-One is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.