Description

4-Benzyl-1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)-1,4-Diazepan-5-One CAS NO 909659-37-6 is a high-purity, advanced pharmaceutical intermediate featuring a unique diazepanone scaffold integrated with a trifluoromethylpyridine moiety. This compound is of significant value for its role in the research and development of novel bioactive molecules, particularly in medicinal chemistry. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex heterocyclic targets.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its privileged heterocyclic structure.
• Agrochemical Synthesis: Intermediate in the development of new active ingredients for crop protection products, leveraging the stability imparted by the trifluoromethyl group.
• Chemical Biology Probe Development: Serves as a scaffold for creating tool compounds to study specific biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scaled-up production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	4-Benzyl-1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)-1,4-Diazepan-5-One
CAS No.	909659-37-6
Molecular Formula	C19H20F3N3O
Molecular Weight	363.38 g/mol
Synonyms	4-Benzyl-1-[(6-(trifluoromethyl)pyridin-3-yl)methyl]-1,4-diazepan-5-one; 1,4-Diazepan-5-one, 4-benzyl-1-[[6-(trifluoromethyl)-3-pyridinyl]methyl]-; 4-Benzyl-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)-1,4-diazepan-5-one; 909659-37-6; 4-Benzyl-1-[(6-trifluoromethylpyridin-3-yl)methyl]-1,4-diazepan-5-one
EINECS	Contact for details

Quality Control

Our 4-Benzyl-1-([6-(Trifluoromethyl)Pyridin-3-Yl]Methyl)-1,4-Diazepan-5-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing all specifications are available upon request. We support development from milligram to kilogram scale with consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.