Description

Defluororac-Linezolid is a key pharmaceutical intermediate, specifically a defluorinated derivative of the oxazolidinone antibiotic linezolid. This compound is of significant value in the research and development of novel antibacterial agents, offering a strategic modification point for medicinal chemists. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of advanced antibiotic candidates and the exploration of new therapeutic pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of next-generation oxazolidinone antibiotics and their analogs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new antibacterial compounds with improved efficacy or reduced resistance.
• API Development: Employed in the process development and scale-up of active pharmaceutical ingredients (APIs) targeting Gram-positive bacterial infections.
• Biochemical Research: Acts as a tool compound for studying bacterial protein synthesis inhibition mechanisms.
• Reference Standard: Can be used as a high-purity analytical standard for quality control in pharmaceutical manufacturing.

Basic Information

Product Name	Defluororac-Linezolid
CAS No.	909570-18-9
Molecular Formula	C16H20FN3O4
Molecular Weight	337.35 g/mol
Synonyms	(S)-N-({3-[3-Fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide; Linezolid Defluorinated Derivative; Linezolid Impurity; UNII-8O5C5VU6QO; 1,3-Oxazolidin-2-one, 5-[[(acetyloxy)amino]methyl]-3-[3-fluoro-4-(4-morpholinyl)phenyl]-, (5R)-; 909570-18-9; Acetamide, N-[[(5S)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-
EINECS	Contact for details

Quality Control

Our Defluororac-Linezolid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.