Description

1-[(1S)-1-(Hydroxymethyl)Propyl]-2-Pyrrolidinone is a high-purity, chiral pyrrolidinone derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel APIs, particularly for central nervous system (CNS) and antiviral drugs.
• Asymmetric Catalyst Ligand Precursor: Used in the development of chiral ligands for metal-catalyzed asymmetric reactions.
• Agrochemical Synthesis: Intermediate for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Building block for high-value specialty chemicals, including liquid crystals and advanced polymers.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	1-[(1S)-1-(Hydroxymethyl)Propyl]-2-Pyrrolidinone
CAS No.	909566-58-1
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	(S)-1-(1-Hydroxymethyl-propyl)-2-pyrrolidinone; (S)-1-(1-Hydroxy-2-methyl-propyl)-2-pyrrolidinone; (S)-1-(2-Methyl-1-hydroxypropyl)-2-pyrrolidinone; (S)-α-Hydroxyisovaleryl pyrrolidine; (S)-1-(1-Hydroxy-2-methylpropyl)pyrrolidin-2-one; 2-Pyrrolidinone, 1-[(1S)-1-(hydroxymethyl)propyl]-; Chiral Hydroxyalkyl Pyrrolidinone
EINECS	Contact for details

Quality Control

Our 1-[(1S)-1-(Hydroxymethyl)Propyl]-2-Pyrrolidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.