Description

4-(2-Amino-1,6-Dihydro-6-Oxo-9H-Purin-9-Yl)-2,5-Anhydro-4-Deoxy-1-(Dimethyl Acetal)-L-Lyxose is a sophisticated nucleoside analogue building block of significant interest in advanced pharmaceutical research and development. Its complex molecular architecture makes it a critical intermediate for the synthesis of novel antiviral and anticancer agents, particularly those targeting viral polymerases and cellular enzymes. This high-purity compound is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries who require reliable, well-characterized raw materials for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral drugs, including potential treatments for hepatitis and other viral infections.
• Anticancer Agent Research: Serves as a building block for developing purine nucleoside analogues that target DNA/RNA synthesis in cancer cells.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand the mechanisms of nucleoside-metabolizing enzymes.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Custom Synthesis: A starting material for the preparation of labeled compounds (e.g., isotopically labeled) for pharmacokinetic and metabolic studies.
• Library Synthesis: Used in combinatorial chemistry to create diverse libraries of nucleoside derivatives for high-throughput screening.

Basic Information

Product Name	4-(2-Amino-1,6-Dihydro-6-Oxo-9H-Purin-9-Yl)-2,5-Anhydro-4-Deoxy-1-(Dimethyl Acetal)-L-Lyxose
CAS No.	909409-94-5
Molecular Formula	C14H20N6O6
Molecular Weight	368.35 g/mol
Synonyms	9-[(4S,5R)-4-Azido-2,2-dimethyl-5-(hydroxymethyl)-1,3-dioxolan-4-yl]-9H-purin-6-amine; L-Lyxose, 4-(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)-2,5-anhydro-4-deoxy-1,1-dimethyl ethyl acetal; 4-Azido-2,2-dimethyl-5-(hydroxymethyl)-1,3-dioxolane-4-carbaldehyde adenosine analogue; Nucleoside analogue intermediate; Purine Lyxose Derivative
EINECS	Contact for details

Quality Control

Every batch of 4-(2-Amino-1,6-Dihydro-6-Oxo-9H-Purin-9-Yl)-2,5-Anhydro-4-Deoxy-1-(Dimethyl Acetal)-L-Lyxose is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting your regulatory filings. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting results from advanced techniques like HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.