Description

2-[(2-Aminophenyl)Thio]Nicotinonitrile is a specialized organic compound featuring a fused aminophenylthio and cyanopyridine structure, serving as a high-value chemical intermediate. Its molecular architecture makes it a critical building block for synthesizing complex heterocyclic compounds, particularly in advanced pharmaceutical research and development. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Material Science Research: Serves as a monomer or building block for developing advanced organic electronic materials, such as organic semiconductors or light-emitting diodes (OLEDs).
• Chemical Biology Probe Development: Utilized in creating specialized molecular probes and inhibitors for studying enzyme mechanisms and cellular pathways.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized dyes and functional pigments due to its conjugated system and reactive sites.
• Academic and Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Item	Detail
Product Name	2-[(2-Aminophenyl)Thio]Nicotinonitrile
CAS No.	909372-42-5
Molecular Formula	C12H9N3S
Molecular Weight	227.28 g/mol
Synonyms	2-[(2-Aminophenyl)sulfanyl]pyridine-3-carbonitrile; 2-((2-Aminophenyl)thio)nicotinonitrile; 3-Cyano-2-[(2-aminophenyl)thio]pyridine; 2-Aminophenyl 3-cyanopyridin-2-yl sulfide; Nicotinonitrile, 2-[(2-aminophenyl)thio]-; 2-(2-Aminophenylthio)-3-cyanopyridine
EINECS	Contact for details

Quality Control

Every batch of 2-[(2-Aminophenyl)Thio]Nicotinonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot and supplied upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.