Description

(S)-tert-Butyl 1-(tert-Butyldimethylsilyloxy)Propan-2-Ylcarbamate is a high-purity, chiral synthetic intermediate of significant importance in advanced organic synthesis. Its value lies in its dual-protected amine and alcohol functionalities, which are crucial for the stereoselective construction of complex molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), peptides, and other fine chemicals where precise chirality control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly for protease inhibitors and other biologically active molecules.
• Peptide Chemistry: Used in the preparation of protected amino acid derivatives for solid-phase and solution-phase peptide synthesis.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material for the construction of stereogenic centers in complex natural products and agrochemicals.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodological studies in organic synthesis and catalysis.
• Custom Synthesis: A critical starting point for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals for clients.

Basic Information

Product Name	(S)-tert-Butyl 1-(tert-Butyldimethylsilyloxy)Propan-2-Ylcarbamate
CAS No.	909297-88-7
Molecular Formula	C14H31NO3Si
Molecular Weight	289.49 g/mol
Synonyms	(S)-2-((tert-Butoxycarbonyl)amino)-1-((tert-butyldimethylsilyl)oxy)propane; (S)-1-((tert-Butyldimethylsilyl)oxy)-2-((tert-butoxycarbonyl)amino)propane; (S)-N-Boc-1-O-TBDMS-propan-2-amine; (S)-tert-Butyl (1-((tert-butyldimethylsilyl)oxy)propan-2-yl)carbamate; Boc-L-Ser(TBDMS)-ol; (S)-2-(Boc-amino)-1-(tert-butyldimethylsilyloxy)propane; 909297-88-7
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 1-(tert-Butyldimethylsilyloxy)Propan-2-Ylcarbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.