Description

Monodesethyl Quinacrine, Dihydrochloride is a high-purity chemical derivative of the antimalarial compound quinacrine, characterized by its dihydrochloride salt form. This compound is of significant interest in pharmaceutical research and development, particularly for its potential as a biochemical tool and a key intermediate in the synthesis of more complex therapeutic agents. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in medicinal chemistry, target validation, and the development of novel pharmacological agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel quinacrine analogs and related compounds for therapeutic research.
• Biochemical Research: Used as a reference standard or active compound in studies investigating cellular mechanisms, enzyme inhibition, and signal transduction pathways.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize drug candidates for improved efficacy and reduced toxicity.
• Antiparasitic Agent Development: Acts as a lead compound or intermediate in the research and development of new agents targeting parasitic diseases.
• In Vitro Diagnostics: May be utilized in the development of assay kits and research reagents for laboratory use.
• Academic Research: Supports fundamental scientific investigations in universities and research institutes focusing on pharmacology and chemical biology.

Basic Information

Product Name	Monodesethyl Quinacrine, Dihydrochloride
CAS No.	908844-46-2
Molecular Formula	C22H28Cl2N3O
Molecular Weight	421.38 g/mol
Synonyms	N1-(6-Chloro-2-methoxy-9-acridinyl)-N4,N4-diethyl-1,4-pentanediamine dihydrochloride; 6-Chloro-9-[(5-diethylamino-2-pentyl)amino]-2-methoxyacridine dihydrochloride; Quinacrine Monodesethyl Dihydrochloride; Desethylquinacrine Dihydrochloride; MDAQ Dihydrochloride
EINECS	Contact for details

Quality Control

Our Monodesethyl Quinacrine, Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation via spectroscopic methods (IR, NMR), and residual solvent analysis to ensure it meets rigorous standards for research and development use. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.