Description

tert-Butyl'(2R,3S)-2-(3-Hydroxypropyl)-3-Methoxymethoxypiperidine-1-Carboxylate is a high-purity chiral piperidine derivative, a critical advanced pharmaceutical intermediate (API) for the synthesis of complex therapeutic agents. Its defined stereochemistry and functional groups make it an essential building block for medicinal chemists developing targeted drug candidates. This compound is primarily utilized in pharmaceutical R&D and manufacturing, particularly for creating novel active pharmaceutical ingredients (APIs) with specific biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug molecules, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Asymmetric Synthesis: Used as a precursor or auxiliary in stereoselective reactions to construct molecules with high enantiomeric purity.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals and bespoke intermediates.

Basic Information

Product Name	tert-Butyl'(2R,3S)-2-(3-Hydroxypropyl)-3-Methoxymethoxypiperidine-1-Carboxylate
CAS No.	908599-39-3
Molecular Formula	C15H29NO5
Molecular Weight	303.40 g/mol
Synonyms	1-Boc-2-[(2R,3S)-2-(3-Hydroxypropyl)-3-Methoxymethoxypiperidine]; (2R,3S)-1-(tert-Butoxycarbonyl)-2-(3-hydroxypropyl)-3-(methoxymethoxy)piperidine; tert-Butyl (2R,3S)-2-(3-hydroxypropyl)-3-[(methoxymethoxy)]-1-piperidinecarboxylate; 908599-39-3; BOC-protected hydroxypropyl methoxymethoxypiperidine; Chiral piperidine-Boc derivative
EINECS	Contact for details

Quality Control

Our tert-Butyl'(2R,3S)-2-(3-Hydroxypropyl)-3-Methoxymethoxypiperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chiral purity and chemical identity, meeting the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.