Description

n-[(1R,2R)-2-[[(1R)-1-(1-Naphthyl)Ethyl]Amino]Cyclohexyl]-4-Nitrobenzenesulfonamide is a high-purity, chiral sulfonamide derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral intermediate or building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific stereochemistry into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in areas requiring enantioselective control.
• Asymmetric Catalyst Ligand Precursor: Used in the development and synthesis of chiral ligands for transition metal-catalyzed asymmetric reactions.
• Organic Synthesis Reagent: Employed in research-scale and process chemistry for constructing complex, stereodefined sulfonamide-containing molecules.
• Agrochemical Research: Intermediate in the development of new, enantiomerically pure pesticides and herbicides.
• Academic & Institutional R&D: A valuable tool for methodological studies in stereochemistry and new reaction development.

Basic Information

Product Name	n-[(1R,2R)-2-[[(1R)-1-(1-Naphthyl)Ethyl]Amino]Cyclohexyl]-4-Nitrobenzenesulfonamide
CAS No.	908598-58-3
Molecular Formula	C24H27N3O4S
Molecular Weight	453.56 g/mol
Synonyms	(1R,2R)-N-[(1R)-1-(1-Naphthyl)ethyl]-N'-(4-nitrophenylsulfonyl)cyclohexane-1,2-diamine; 4-Nitro-N-[(1R,2R)-2-[[(1R)-1-(1-naphthyl)ethyl]amino]cyclohexyl]benzenesulfonamide; (1R,2R)-2-[(R)-1-(Naphthalen-1-yl)ethylamino]cyclohexyl 4-nitrobenzenesulfonamide; Chiral Sulfonamide Intermediate 908598-58-3
EINECS	Contact for details

Quality Control

Our n-[(1R,2R)-2-[[(1R)-1-(1-Naphthyl)Ethyl]Amino]Cyclohexyl]-4-Nitrobenzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (HPLC), chemical purity (HPLC), and identity confirmation (NMR, IR, MS) to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.