Description

(S)-2-Amino-3-(3-Aminophenyl)Propanoic Acid Dihydrochloride is a high-purity, non-natural amino acid derivative of significant interest in advanced pharmaceutical research and development. This chiral compound serves as a critical building block for the synthesis of complex molecules, particularly peptidomimetics and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in drug discovery, process development, and the production of specialized biochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel therapeutic agents, including protease inhibitors and receptor modulators.
• Peptidomimetic Research: Used to incorporate modified phenylalanine analogs into peptide chains to enhance stability, bioavailability, and target specificity.
• Chemical Biology Probes: Employed in the development of labeled compounds and probes for studying enzyme mechanisms and protein-protein interactions.
• Asymmetric Synthesis: Serves as a valuable starting material or auxiliary in catalytic asymmetric reactions to construct complex chiral centers.
• API Development: Integral to the research-scale and pre-clinical development of new chemical entities (NCEs) targeting central nervous system and metabolic disorders.

Basic Information

Product Name	(S)-2-Amino-3-(3-Aminophenyl)Propanoic Acid Dihydrochloride
CAS No.	908571-75-5
Molecular Formula	C9H14Cl2N2O2
Molecular Weight	253.13 g/mol
Synonyms	(S)-3-Amino-L-phenylalanine dihydrochloride; (S)-2-Amino-3-(3-aminophenyl)propanoic acid hydrochloride (1:2); L-3-Amino-phenylalanine 2HCl; (S)-3-Amino-Phe-OH·2HCl; 3-Amino-L-Phe 2HCl; 3-Amino-DL-phenylalanine dihydrochloride (related); 3-Aminophenylalanine dihydrochloride
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-3-(3-Aminophenyl)Propanoic Acid Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.