Description

Ethyl 6-(2-Furyl)-4-Oxo-2-[4-(2-Pyrimidinyl)-1-Piperazinyl]-1,4,5,6-Tetrahydro-5-Pyrimidinecarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and cardiovascular disorders. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for developing next-generation therapeutic candidates and for process optimization in regulated synthesis pathways.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of proprietary drug candidates, especially in neurological and cardiovascular research.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Development: Employed in the pilot-scale and commercial-scale production of Active Pharmaceutical Ingredients requiring a fused pyrimidine-piperazine core.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical companies with custom synthesis and process development.
• Chemical Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in API manufacturing.
• Academic Research: Used in university and institutional labs for studying heterocyclic chemistry, reaction mechanisms, and new synthetic methodologies.

Basic Information

Product Name	Ethyl 6-(2-Furyl)-4-Oxo-2-[4-(2-Pyrimidinyl)-1-Piperazinyl]-1,4,5,6-Tetrahydro-5-Pyrimidinecarboxylate
CAS No.	908497-08-5
Molecular Formula	C19H22N6O4
Molecular Weight	398.42 g/mol
Synonyms	Ethyl 6-(2-furyl)-4-oxo-2-[4-(2-pyrimidinyl)-1-piperazinyl]-1,4,5,6-tetrahydro-5-pyrimidinecarboxylate; 5-Pyrimidinecarboxylic acid, 1,4,5,6-tetrahydro-6-(2-furanyl)-4-oxo-2-[4-(2-pyrimidinyl)-1-piperazinyl]-, ethyl ester; 908497-08-5; UNII-8V6F7T8U4N; 8V6F7T8U4N; Ethyl 6-(furan-2-yl)-4-oxo-2-(4-(pyrimidin-2-yl)piperazin-1-yl)-1,4,5,6-tetrahydro-5-pyrimidinecarboxylate; SCHEMBL15450427; ZINC000006889676
EINECS	Contact for details

Quality Control

Our Ethyl 6-(2-Furyl)-4-Oxo-2-[4-(2-Pyrimidinyl)-1-Piperazinyl]-1,4,5,6-Tetrahydro-5-Pyrimidinecarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.