Description

2-(3-Carboxy-Phenyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it provides a protected carboxylic acid group and a piperidine scaffold, enabling precise and efficient multi-step organic synthesis. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS).
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its complex heterocyclic structure.
• Organic Synthesis: Serves as a versatile precursor for constructing more complex molecules in academic and industrial research laboratories.
• Peptidomimetics: The piperidine and protected carboxylate moieties make it valuable for creating peptide-like compounds with enhanced stability.
• Chemical Reference Standard: Utilized as a high-purity standard for analytical method development and quality control in API manufacturing.
• Material Science: Potential precursor for specialty polymers and functional materials requiring specific molecular architectures.

Basic Information

Item	Details
Product Name	2-(3-Carboxy-Phenyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	908334-24-7
Molecular Formula	C18H23NO4
Molecular Weight	317.38 g/mol
Synonyms	tert-Butyl 2-(3-carboxyphenyl)piperidine-1-carboxylate; 1-Boc-2-(3-carboxyphenyl)piperidine; 2-(3-Carboxyphenyl)piperidine-1-carboxylic acid 1,1-dimethylethyl ester; 908334-24-7; 2-(3-Carboxy-Phenyl)-Piperidine-1-Carboxylic Acid 1,1-Dimethylethyl Ester; 1-(tert-Butoxycarbonyl)-2-(3-carboxyphenyl)piperidine; Boc-2-(3-COOH-Ph)-piperidine
EINECS	Contact for details

Quality Control

Our 2-(3-Carboxy-Phenyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP standards and reliable documentation supports your regulatory and supply chain requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.