Description

2-(1-(tert-Butoxycarbonyl)Piperidin-3-Yl)Benzoic Acid is a high-purity, advanced pharmaceutical intermediate featuring a benzoic acid moiety linked to a protected piperidine ring. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of complex small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Synthesis: Serves as a core structural component in the development of protease inhibitors and other enzyme-targeted therapies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.
• Academic Research: Employed in university and institutional laboratories for studying organic synthesis methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-(1-(tert-Butoxycarbonyl)Piperidin-3-Yl)Benzoic Acid
CAS No.	908334-22-5
Molecular Formula	C17H23NO4
Molecular Weight	305.37 g/mol
Synonyms	2-[1-[(2-Methylpropan-2-yl)oxycarbonyl]piperidin-3-yl]benzoic acid; 2-(1-Boc-piperidin-3-yl)benzoic acid; 2-(3-Piperidyl)benzoic acid 1-Boc derivative; 2-(1-N-Boc-3-piperidyl)benzoic acid; 908334-22-5; tert-Butyl 3-(2-carboxyphenyl)piperidine-1-carboxylate; 1-Boc-3-(2-carboxyphenyl)piperidine
EINECS	Contact for details

Quality Control

Our 2-(1-(tert-Butoxycarbonyl)Piperidin-3-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with client specifications and relevant industry standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.