Description

3-(1-(tert-Butoxycarbonyl)Azetidin-3-Yl)Benzoic Acid is a high-purity, advanced pharmaceutical intermediate featuring a benzoic acid scaffold linked to a protected azetidine ring. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring complex heterocyclic architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Protease Inhibitor Research: Used in the development of protease inhibitors, where the azetidine moiety can act as a crucial pharmacophore.
• Chemical Biology & Probe Development: Employed in the creation of chemical probes for studying biological pathways and target validation.
• Peptidomimetic Synthesis: Serves as a constrained scaffold in the design of peptidomimetics to improve metabolic stability and bioavailability.
• Library Synthesis for High-Throughput Screening: Utilized in combinatorial chemistry to generate diverse compound libraries for biological screening.
• Agrochemical Research: Potential intermediate in the development of new agrochemicals with specific biological activity.

Basic Information

Product Name	3-(1-(tert-Butoxycarbonyl)Azetidin-3-Yl)Benzoic Acid
CAS No.	908334-11-2
Molecular Formula	C15H19NO4
Molecular Weight	277.32 g/mol
Synonyms	3-[1-[(2-Methylpropan-2-yl)oxycarbonyl]azetidin-3-yl]benzoic acid; 3-(1-Boc-azetidin-3-yl)benzoic acid; 1-Boc-3-(3-carboxyphenyl)azetidine; Benzoic acid, 3-[1-[[(1,1-dimethylethoxy)carbonyl]-3-azetidinyl]-; 3-(1-Boc-3-azetidinyl)benzoic acid; 3-(Azetidin-3-yl)benzoic acid tert-butyl carbamate; tert-Butyl 3-(3-carboxyphenyl)azetidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 3-(1-(tert-Butoxycarbonyl)Azetidin-3-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.