Description

4,6-Diamino-3-Iodo-1-(β-D-Ribofuranosyl)-1H-Pyrazolo[3,4-D]Pyrimidine is a specialized nucleoside analog with a unique pyrazolopyrimidine scaffold modified with an iodine atom. This compound is of significant interest in pharmaceutical research and development, particularly as a key intermediate or building block for novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of antiviral and anticancer drug candidates, where its structural features enable targeted molecular interactions.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel nucleoside analog drugs targeting viral polymerases.
• Antiviral Research: Used in the development of potential therapeutics for viral infections, leveraging its modified ribose and halogenated base structure.
• Oncology Drug Discovery: Serves as a precursor in creating compounds that may inhibit key enzymes involved in cancer cell proliferation.
• Biochemical Probe: Employed in enzymatic studies to investigate substrate specificity and inhibition mechanisms of purine-metabolizing enzymes.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of drug candidates.
• Academic Research: Utilized in universities and research institutes for fundamental studies in nucleotide chemistry and biochemistry.

Basic Information

Product Name	4,6-Diamino-3-Iodo-1-(β-D-Ribofuranosyl)-1H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	908143-13-5
Molecular Formula	C10H13IN6O4
Molecular Weight	408.15 g/mol
Synonyms	3-Iodo-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine; 4,6-Diamino-3-iodo-1-β-D-ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidine; 3-Iodopyrazolopyrimidine ribonucleoside; 908143-13-5; 1-(β-D-Ribofuranosyl)-4,6-diamino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine; Iodinated Pyrazolopyrimidine Nucleoside; 4,6-Diamino-3-iodo-1-(β-D-ribofuranosyl)pyrazolo[3,4-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4,6-Diamino-3-Iodo-1-(β-D-Ribofuranosyl)-1H-Pyrazolo[3,4-D]Pyrimidine is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.