Description

Methyl (2S)-2-Amino-2-(4-Benzyloxyphenyl)Acetate is a high-purity chiral amino acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules with high enantiomeric purity. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel APIs, especially in central nervous system (CNS) and metabolic disorder drug candidates.
• Peptidomimetics Research: Used in the design and synthesis of peptide analogs and non-peptide scaffolds for drug discovery programs.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to introduce chirality.
• Protease Inhibitor Development: A valuable precursor for creating inhibitors targeting specific enzymes like proteases.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds or molecular probes for studying biological pathways.
• Fine Chemical Production: Serves as a building block for specialty chemicals, agrochemicals, and advanced materials requiring specific stereochemistry.

Basic Information

Product Name	Methyl (2S)-2-Amino-2-(4-Benzyloxyphenyl)Acetate
CAS No.	908066-52-4
Molecular Formula	C16H17NO3
Molecular Weight	271.31 g/mol
Synonyms	(S)-Methyl 2-amino-2-(4-(benzyloxy)phenyl)acetate; L-4-Benzyloxyphenylglycine methyl ester; Methyl (S)-2-amino-2-[4-(phenylmethoxy)phenyl]acetate; (2S)-2-Amino-2-[4-(benzyloxy)phenyl]acetic acid methyl ester; Methyl O-benzyl-L-tyrosinate; (S)-α-Amino-4-(benzyloxy)benzeneacetic acid methyl ester; 908066-52-4; BOC-L-Tyr(Bzl)-OMe precursor
EINECS	Contact for details

Quality Control

Our Methyl (2S)-2-Amino-2-(4-Benzyloxyphenyl)Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.