Description

5,7-Difluoro-1,2,3,4-Tetrahydro-Naphthalen-1-Ylamine Hydrochloride is a high-purity, fluorinated amine hydrochloride salt serving as a critical building block in advanced organic synthesis. Its value lies in providing a rigid, functionalized tetralin scaffold with fluorine atoms that can dramatically influence the biological activity and metabolic stability of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of central nervous system (CNS) and cardiovascular drug candidates, where the fluorinated tetralin core modulates receptor binding.
• Agrochemical Synthesis: Used in constructing advanced herbicides and fungicides, leveraging the fluorine atoms to enhance lipophilicity and environmental stability.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating fluorescent tags or affinity probes to study enzyme function and protein interactions.
• Material Science Research: Acts as a monomer or precursor for specialty polymers and liquid crystals, where its structure contributes to specific optical or electronic properties.
• Academic & Contract Research: Employed in methodological studies and custom synthesis projects requiring sophisticated, fluorinated amine chemistry.

Basic Information

Product Name	5,7-Difluoro-1,2,3,4-Tetrahydro-Naphthalen-1-Ylamine Hydrochloride
CAS No.	907973-46-0
Molecular Formula	C₁₀H₁₂ClF₂N
Molecular Weight	219.66 g/mol
Synonyms	1-Amino-5,7-difluoro-1,2,3,4-tetrahydronaphthalene hydrochloride; 5,7-Difluoro-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride; 1-(5,7-Difluoro-3,4-dihydronaphthalen-1(2H)-yl)amine hydrochloride; 5,7-Difluoro-1-amino-1,2,3,4-tetrahydronaphthalene HCl; 1,2,3,4-Tetrahydro-5,7-difluoronaphthalen-1-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 5,7-Difluoro-1,2,3,4-Tetrahydro-Naphthalen-1-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.