Description

(±)-trans-o-tert-Butyl-n-(2-(4-Bromophenyl)Cyclopropyl)Carbamate is a high-purity, advanced pharmaceutical intermediate characterized by its unique cyclopropyl and bromophenyl functional groups. This compound is of significant value for its role as a key building block in the synthesis of complex, biologically active molecules, offering precise stereochemistry and functional group compatibility. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to explore new chemical entities.
• Process Chemistry Development: Serves as a standardized building block for scaling up synthetic routes from laboratory to pilot plant scale.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the production of bespoke compounds for client projects.
• Academic Research: Utilized in university laboratories for methodological studies in organic synthesis and catalysis involving strained ring systems.

Basic Information

Product Name	(±)-trans-o-tert-Butyl-n-(2-(4-Bromophenyl)Cyclopropyl)Carbamate
CAS No.	907196-11-6
Molecular Formula	C₁₄H₁₈BrNO₂
Molecular Weight	312.20 g/mol
Synonyms	tert-Butyl N-[(1R,2S)-2-(4-bromophenyl)cyclopropyl]carbamate (trans-); (1R,2S)-rel-2-(4-Bromophenyl)cyclopropanamine N-BOC derivative; trans-2-(4-Bromophenyl)cyclopropylcarbamic acid tert-butyl ester; BOC-Protected 2-(4-Bromophenyl)cyclopropylamine (trans-); N-Boc-2-(4-bromophenyl)cyclopropanamine (trans racemate); 907196-11-6; Carbamic acid, N-[2-(4-bromophenyl)cyclopropyl]-, 1,1-dimethylethyl ester, (1R,2S)-rel-
EINECS	Contact for details

Quality Control

Our (±)-trans-o-tert-Butyl-n-(2-(4-Bromophenyl)Cyclopropyl)Carbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with complete chromatographic data and spectroscopic profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; ensure the container is kept sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.